INT342077

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Context Info
Confidence 0.32
First Reported 2010
Last Reported 2010
Negated 2
Speculated 0
Reported most in Body
Documents 1
Total Number 5
Disease Relevance 3.58
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Lat) plasma membrane (Lat) intracellular (Lat)
Lat (Mus musculus)
Pain Link Frequency Relevance Heat
ketamine 10 5.00 Very Low Very Low Very Low
monoamine 5 5.00 Very Low Very Low Very Low
Pain 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cold Sores 445 99.84 Very High Very High Very High
Sprains And Strains 225 96.08 Very High Very High Very High
Infection 55 91.52 High High
Herpes Simplex Virus 5 81.04 Quite High
Eye Infections 5 20.96 Low Low
Body Weight 10 5.00 Very Low Very Low Very Low
Systemic Lupus Erythematosus 10 5.00 Very Low Very Low Very Low
Pain 5 5.00 Very Low Very Low Very Low
Overdose 5 5.00 Very Low Very Low Very Low
Repression 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast, when the same experimental protocol was applied to rabbits latent with HSV-1 strain KOS, with the goal being to determine whether we could observe a difference in the patterns of enrichment of H3K4me2 associated with the LAT region of KOS following TCIE of latently infected rabbits, we found no significant change (either increase or decrease) in the overall enrichment of H3K4me2 for the LAT 5?
Positive_regulation (overall) of Neg (no) Gene_expression (overall) of LAT 5 associated with cold sores and sprains and strains
1) Confidence 0.32 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2973973 Disease Relevance 0.94 Pain Relevance 0
However, the exact mechanism of the LAT in reactivation of HSV-1 has yet to be elucidated.
Positive_regulation (reactivation) of Gene_expression (mechanism) of LAT associated with cold sores
2) Confidence 0.32 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2973973 Disease Relevance 1.08 Pain Relevance 0
In contrast, when the same experimental protocol was applied to rabbits latent with HSV-1 strain KOS, with the goal being to determine whether we could observe a difference in the patterns of enrichment of H3K4me2 associated with the LAT region of KOS following TCIE of latently infected rabbits, we found no significant change (either increase or decrease) in the overall enrichment of H3K4me2 for the LAT 5?
Positive_regulation (enrichment) of Neg (no) Gene_expression (overall) of LAT 5 associated with cold sores and sprains and strains
3) Confidence 0.32 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2973973 Disease Relevance 0.94 Pain Relevance 0
Primer and probe sequences used for LAT 5?
Positive_regulation (sequences) of Gene_expression (used) of LAT 5
4) Confidence 0.32 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2973973 Disease Relevance 0 Pain Relevance 0
exon, with a significant (P<0.05) 2.5-fold reduction in the overall H3K4me2enrichment of LAT 5?
Positive_regulation (overall) of Gene_expression (overall) of LAT 5
5) Confidence 0.28 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2973973 Disease Relevance 0.63 Pain Relevance 0

General Comments

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