INT342181

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.76
Pain Relevance 0.41

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Ros1) cell proliferation (Ros1) signal transduction (Ros1)
extracellular region (Igfals) cell adhesion (Igfals) nucleus (Igfals)
Anatomy Link Frequency
neuronal 1
Igfals (Mus musculus)
Ros1 (Mus musculus)
Pain Link Frequency Relevance Heat
Glutamate 5 100.00 Very High Very High Very High
cytokine 13 96.66 Very High Very High Very High
Spinal cord 30 83.76 Quite High
Central nervous system 12 76.36 Quite High
Inflammation 26 75.64 Quite High
medulla 19 74.16 Quite High
Multiple sclerosis 6 37.84 Quite Low
Pain 3 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Motor Neuron Diseases 42 100.00 Very High Very High Very High
Parkinson's Disease 6 98.40 Very High Very High Very High
Targeted Disruption 13 89.80 High High
Death 12 80.24 Quite High
INFLAMMATION 26 75.64 Quite High
Toxicity 1 48.00 Quite Low
Disease 17 44.24 Quite Low
Autoimmune Disease 1 39.08 Quite Low
Demyelinating Disease 6 37.84 Quite Low
Paralysis 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Accordingly, a reduced number of astrocytes and diminished cytokine levels positively influenced neuronal survival and inhibited mitochondrial dysfunction which otherwise might have led to increased levels of reactive oxygen species (ROS) and glutamate release associated with ALS [37].
ALS Binding (associated) of ROS in neuronal associated with parkinson's disease, glutamate, motor neuron diseases and cytokine
1) Confidence 0.01 Published 2010 Journal J Neuroinflammation Section Body Doc Link PMC2974667 Disease Relevance 0.76 Pain Relevance 0.41

General Comments

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