INT342200

Context Info Confidence 0.06 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 2 Total Number 3 Disease Relevance 2.66 Pain Relevance 0.05

extracellular region (Gnptg) Golgi apparatus (Gnptg)

Anatomy Link Frequency lymphocyte 2 Gnptg (Mus musculus)

Pain Link Frequency Relevance Heat cytokine 7 50.44 Inflammation 31 50.08 alcohol 5 40.40 metalloproteinase 36 5.00 halothane 6 5.00 tolerance 6 5.00 fibrosis 4 5.00 sSRI 2 5.00 Paracetamol 2 5.00 Bile 2 5.00

Disease Link Frequency Relevance Heat Autoimmune Hepatitis 137 99.96 Sprains And Strains 16 98.00 Toxicity 18 84.40 Obesity 2 77.36 Autoimmune Disease 38 75.84 Injury 14 75.12 Body Weight 6 71.64 Attention Deficit Hyperactivity Disorder 2 55.88 INFLAMMATION 29 50.08 Hepatitis 17 28.24

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

TCA concentrations were significantly lower and TCE concentrations tended to be higher in exposed Ppar?

Positive_regulation (tended) of Gene_expression (concentrations) of TCE

1) Confidence 0.06 Published 2010 Journal Environ Health Perspect Section Body Doc Link PMC2974693 Disease Relevance 0.44 Pain Relevance 0

Taken together these results showed that TCE exposure induced AIH, complete with lymphocyte infiltration and generation of antiliver antibodies, in MRL+/+ mice. 7.

Positive_regulation (induced) of Gene_expression (exposure) of TCE in lymphocyte associated with autoimmune hepatitis

2) Confidence 0.04 Published 2010 Journal Hepatitis Research and Treatment Section Body Doc Link PMC3021850 Disease Relevance 1.08 Pain Relevance 0

TCE exposure in mice also expanded the percentage of activated IFN-?

Positive_regulation (expanded) of Gene_expression (exposure) of TCE

3) Confidence 0.03 Published 2010 Journal Hepatitis Research and Treatment Section Body Doc Link PMC3021850 Disease Relevance 1.15 Pain Relevance 0.05

General Comments

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