INT342207

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Context Info
Confidence 0.25
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.51
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Cyp2e1) oxidoreductase activity (Cyp2e1) endoplasmic reticulum (Cyp2e1)
enzyme binding (Cyp2e1)
Cyp2e1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 9 52.48 Quite High
agonist 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Toxicity 6 85.76 High High
Stress 1 83.60 Quite High
Sprains And Strains 16 77.92 Quite High
Hepatotoxicity 2 77.36 Quite High
Necrosis 7 53.52 Quite High
INFLAMMATION 9 52.48 Quite High
Body Weight 6 5.00 Very Low Very Low Very Low
Injury 6 5.00 Very Low Very Low Very Low
Hepatomegaly 4 5.00 Very Low Very Low Very Low
Hypertrophy 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
TRI exposure did not influence hepatic CYP2E1 expression, but it did decrease ALDH2 expression to a comparable extent in all mouse lines (data not shown).


Neg (not) Regulation (influence) of Gene_expression (expression) of CYP2E1
1) Confidence 0.25 Published 2010 Journal Environ Health Perspect Section Body Doc Link PMC2974693 Disease Relevance 0.51 Pain Relevance 0.03

General Comments

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