INT342226

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.34
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Aldh3a1) oxidoreductase activity (Aldh3a1) endoplasmic reticulum (Aldh3a1)
cytoplasm (Aldh3a1)
TRNAI1 (Homo sapiens)
Aldh3a1 (Mus musculus)
Pain Link Frequency Relevance Heat
Agonist 2 85.76 High High
Inflammatory 9 5.00 Very Low Very Low Very Low
Cytokine 1 5.00 Very Low Very Low Very Low
Anesthesia 1 5.00 Very Low Very Low Very Low
Alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sprains And Strains 16 95.32 Very High Very High Very High
Hepatomegaly 4 63.36 Quite High
Body Weight 6 57.32 Quite High
Hypertrophy 2 39.80 Quite Low
INFLAMMATION 9 5.00 Very Low Very Low Very Low
Necrosis 7 5.00 Very Low Very Low Very Low
Toxicity 6 5.00 Very Low Very Low Very Low
Injury 6 5.00 Very Low Very Low Very Low
Rhinitis 2 5.00 Very Low Very Low Very Low
Hepatotoxicity 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To clarify the mechanism underlying the lower TCA levels, we measured expression of the ALDH2 protein involved in the metabolism of chloral hydrate to TCA because TRI has been reported to inhibit ALDH expression and activity (Wang et al. 1999); we found that ALDH2 was reduced to the same degree after TRI exposure in all three strains of mice.
TRI Negative_regulation (inhibit) of Gene_expression (expression) of ALDH associated with sprains and strains
1) Confidence 0.02 Published 2010 Journal Environ Health Perspect Section Body Doc Link PMC2974693 Disease Relevance 0.34 Pain Relevance 0.04

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox