INT342362

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Context Info
Confidence 0.15
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Irs1, Rara) signal transduction (Irs1, Rara) nucleus (Irs1, Rara)
enzyme binding (Rara) DNA binding (Rara) signal transducer activity (Irs1)
Anatomy Link Frequency
immune system 1
Irs1 (Mus musculus)
Rara (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 6 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Aging 49 50.00 Quite Low
Sprains And Strains 2 11.68 Low Low
Stress 14 5.00 Very Low Very Low Very Low
Disease 11 5.00 Very Low Very Low Very Low
Age-related Macular Degeneration 9 5.00 Very Low Very Low Very Low
INFLAMMATION 7 5.00 Very Low Very Low Very Low
Retinal Diseases 6 5.00 Very Low Very Low Very Low
Retina Disease 3 5.00 Very Low Very Low Very Low
Apoptosis 3 5.00 Very Low Very Low Very Low
Hypoxia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The list of validated genes includes those associated with retinoic acid receptor (RAR) signaling - retinol dehydrogenase 9 (Rdh9); immune system regulation - histocompatibility 2 K1, K region (H2-K1), interferon regulatory factor 6 (Irf6), and endoplasmic reticulum aminopeptidase 1 (Erap1); lipid and insulin metabolism - stearoyl coenzyme A desaturase (Scd1), oxysterol binding protein-like 1A (Osbpl1a), and insulin receptor substrate 1 (Irs1); and two genes that have not yet been characterized (Ai117581, Riken C030034E14).
insulin receptor substrate 1 Binding (associated) of RAR in immune system
1) Confidence 0.15 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2975639 Disease Relevance 0 Pain Relevance 0

General Comments

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