INT342518

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Context Info
Confidence 0.04
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.40
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

unfolded protein binding (HSP90B1) endoplasmic reticulum (HSP90B1) intracellular (TLR4)
cytoplasm (TLR4) response to stress (HSP90B1) cytosol (HSP90B1)
HSP90B1 (Homo sapiens)
TLR4 (Homo sapiens)
Pain Link Frequency Relevance Heat
Crohn's disease 51 99.92 Very High Very High Very High
Inflammation 5 69.20 Quite High
cytokine 3 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 55 99.92 Very High Very High Very High
Sprains And Strains 27 78.96 Quite High
INFLAMMATION 5 69.20 Quite High
Targeted Disruption 2 67.20 Quite High
Stress 17 50.00 Quite Low
Pseudomonas Infection 1 28.04 Quite Low
Inflammatory Bowel Disease 12 5.00 Very Low Very Low Very Low
Infection 8 5.00 Very Low Very Low Very Low
Adhesions 4 5.00 Very Low Very Low Very Low
Meningitis 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Gp96 participates in the folding and assembly of many secretory and membrane proteins and has been shown to be essential for the cell surface expression of Toll-like receptors (TLRs), including TLR2 and TLR4.45 Therefore, we can consider whether it participates in the cell membrane targeting of CEACAM6.
Gp96 Positive_regulation (essential) of Gene_expression (expression) of TLR4
1) Confidence 0.04 Published 2010 Journal Gut Section Body Doc Link PMC2976078 Disease Relevance 0.40 Pain Relevance 0.13

General Comments

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