INT342571

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.12
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 7
Disease Relevance 8.05
Pain Relevance 0.67

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (NUDT6) nucleus (NUDT6) cellular_component (NUDT6)
biological_process (NUDT6) cytoplasm (NUDT6)
Anatomy Link Frequency
lamina 2
NUDT6 (Homo sapiens)
Pain Link Frequency Relevance Heat
fibrosis 28 95.36 Very High Very High Very High
cytokine 35 86.96 High High
Crohn's disease 35 39.12 Quite Low
chemokine 14 5.44 Low Low
Inflammation 35 5.00 Very Low Very Low Very Low
Nerve growth factor 28 5.00 Very Low Very Low Very Low
abdominal pain 7 5.00 Very Low Very Low Very Low
antagonist 7 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Eosinophilic Esophagitis 742 100.00 Very High Very High Very High
Gastroesophageal Reflux Disease 252 100.00 Very High Very High Very High
Cicatrix 7 96.92 Very High Very High Very High
Fibrosis 42 95.36 Very High Very High Very High
Disease 126 86.64 High High
Dysphagia 21 86.20 High High
Injury 14 79.72 Quite High
Hypersensitivity 28 66.40 Quite High
General Immunology 7 53.88 Quite High
Inflammatory Bowel Disease 35 37.80 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In comparison to a previous study showing that EoE subjects have an increase in local FGF production [25], our study demonstrates that there is increase in FGF production locally and this increase is also reflected systemically.
Positive_regulation (increase) of Gene_expression (production) of FGF associated with eosinophilic esophagitis
1) Confidence 0.12 Published 2010 Journal Allergy Asthma Clin Immunol Section Body Doc Link PMC2976489 Disease Relevance 1.44 Pain Relevance 0.17
Although FGF levels in GERD subjects were slightly elevated (n = 8), it was not statistically significant compared to HC (p > 0.05) (Figure 1a).
Positive_regulation (elevated) of Gene_expression (levels) of FGF associated with gastroesophageal reflux disease
2) Confidence 0.12 Published 2010 Journal Allergy Asthma Clin Immunol Section Body Doc Link PMC2976489 Disease Relevance 0.94 Pain Relevance 0
In comparison to a previous study showing that EoE subjects have an increase in local FGF production [25], our study demonstrates that there is increase in FGF production locally and this increase is also reflected systemically.
Positive_regulation (increase) of Gene_expression (production) of FGF associated with eosinophilic esophagitis
3) Confidence 0.12 Published 2010 Journal Allergy Asthma Clin Immunol Section Body Doc Link PMC2976489 Disease Relevance 1.55 Pain Relevance 0.18
Initial immunohistochemistry antibody stains of FGF demonstrate an increase in local esophageal FGF expression levels in the lamina propria.
Positive_regulation (increase) of Gene_expression (expression) of FGF in lamina
4) Confidence 0.12 Published 2010 Journal Allergy Asthma Clin Immunol Section Body Doc Link PMC2976489 Disease Relevance 0.57 Pain Relevance 0
While healthy control and GERD subjects have very low expression of FGF, EoE subjects show higher FGF expression.
Positive_regulation (higher) of Gene_expression (expression) of FGF associated with gastroesophageal reflux disease and eosinophilic esophagitis
5) Confidence 0.08 Published 2010 Journal Allergy Asthma Clin Immunol Section Body Doc Link PMC2976489 Disease Relevance 0.98 Pain Relevance 0.05
These data further suggested that FGF expression levels may help differentiate EoE from GERD, since EoE subjects have a significantly higher FGF expression level than GERD.
Positive_regulation (level) of Gene_expression (expression) of FGF associated with gastroesophageal reflux disease and eosinophilic esophagitis
6) Confidence 0.08 Published 2010 Journal Allergy Asthma Clin Immunol Section Body Doc Link PMC2976489 Disease Relevance 1.29 Pain Relevance 0.13
These data further suggested that FGF expression levels may help differentiate EoE from GERD, since EoE subjects have a significantly higher FGF expression level than GERD.
Positive_regulation (level) of Gene_expression (expression) of FGF associated with gastroesophageal reflux disease and eosinophilic esophagitis
7) Confidence 0.08 Published 2010 Journal Allergy Asthma Clin Immunol Section Body Doc Link PMC2976489 Disease Relevance 1.27 Pain Relevance 0.13

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox