INT342616

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Context Info
Confidence 0.56
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.75
Pain Relevance 0.81

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Timp2) nucleus (Timp2)
Timp2 (Mus musculus)
Pain Link Frequency Relevance Heat
palliative 86 98.16 Very High Very High Very High
metalloproteinase 16 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Metastasis 48 99.48 Very High Very High Very High
Cancer 72 99.14 Very High Very High Very High
Hepatocellular Cancer 116 97.28 Very High Very High Very High
Lifespan 16 81.64 Quite High
Residual Neoplasm 6 5.00 Very Low Very Low Very Low
Anaemia 2 5.00 Very Low Very Low Very Low
Body Weight 2 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low
Dislocations 2 5.00 Very Low Very Low Very Low
Thrombocytopenia 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Palliative resection enhances MMP2 activity, elevates tumor protein levels of MMP2 and VEGF, and down-regulates TIMP2 in situ
Regulation (regulates) of TIMP2 associated with cancer and palliative
1) Confidence 0.56 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2976755 Disease Relevance 0.59 Pain Relevance 0.59
Based on our in vitro and in vivo studies, we considered that inhibition of the metastasis-enhancing effects due to dysregulation of MMP2/TIMP2 and VEGF might further improve operative efficacy in patients with HCC.
Regulation (dysregulation) of TIMP2 associated with hepatocellular cancer and metastasis
2) Confidence 0.25 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2976755 Disease Relevance 1.16 Pain Relevance 0.22

General Comments

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