INT342647

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Context Info
Confidence 0.37
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.64
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Avp, Crh) extracellular region (Avp, Crh) response to stress (Avp, Crh)
signal transduction (Avp) cytoplasm (Crh) signal transducer activity (Avp)
Anatomy Link Frequency
SCN 2
Avp (Rattus norvegicus)
Crh (Rattus norvegicus)
Pain Link Frequency Relevance Heat
depression 29 95.92 Very High Very High Very High
corticosteroid 1 60.48 Quite High
Dopamine 5 12.96 Low Low
Serotonin 7 5.00 Very Low Very Low Very Low
sSRI 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Neuropeptide 2 5.00 Very Low Very Low Very Low
monoamine 2 5.00 Very Low Very Low Very Low
cocaine 1 5.00 Very Low Very Low Very Low
Neurotransmitter 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Depression 35 95.92 Very High Very High Very High
Stress 4 77.52 Quite High
Nicotine Addiction 1 77.36 Quite High
Affective Disorder 4 48.40 Quite Low
Anxiety Disorder 11 42.52 Quite Low
Neurosis 7 5.00 Very Low Very Low Very Low
Genetic Predisposition To Disease 3 5.00 Very Low Very Low Very Low
Mental Disorders 3 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The schematic figure illustrates the impaired interaction among the decreased activity of vasopressin neurons (AVP) in the suprachiasmatic nucleus (SCN), the increased activity of corticotropin-releasing hormone (CRH) neurons in the paraventricular nucleus (PVN), the increased release of adrenocorticotropin (ACTH) into the blood stream by the pituitary gland, and the increased release of cortisol by the adrenal gland.
Negative_regulation (impaired) of AVP Neg (impaired) Binding (interaction) of corticotropin-releasing hormone in SCN
1) Confidence 0.37 Published 2010 Journal Qual Life Res Section Body Doc Link PMC2977055 Disease Relevance 0.64 Pain Relevance 0.18

General Comments

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