INT342657

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Context Info
Confidence 0.07
First Reported 2010
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.29
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Tfrc) peptidase activity (Tfrc) mitochondrion (Tfrc)
aging (Tfrc) extracellular region (Tfrc) cytoplasmic membrane-bounded vesicle (Tfrc)
Anatomy Link Frequency
liver 2
Tfrc (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Central nervous system 2 28.44 Quite Low
cytokine 28 5.00 Very Low Very Low Very Low
Bile 2 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
dexamethasone 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Body Weight 2 84.80 Quite High
Diabetes Mellitus 2 81.96 Quite High
Targeted Disruption 4 64.04 Quite High
Injury 12 5.00 Very Low Very Low Very Low
Abscess 4 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low
Hepatocellular Cancer 2 5.00 Very Low Very Low Very Low
Alzheimer's Dementia 2 5.00 Very Low Very Low Very Low
Hepatotoxicity 2 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This may be attributable not only to a reduced TH serum level, but also to the direct effect of acute-phase mediators on the regulation of the TR gene expression in liver cells, possibly explaining the lack of clinical effectiveness of T3 administration under acute-phase conditions.


Regulation (regulation) of Gene_expression (expression) of TR in liver
1) Confidence 0.07 Published 2010 Journal Cell Tissue Res Section Body Doc Link PMC2977073 Disease Relevance 0.29 Pain Relevance 0
Immunohistology revealed no significant change in the protein expression of TR?
Neg (no) Regulation (change) of Gene_expression (expression) of TR
2) Confidence 0.07 Published 2010 Journal Cell Tissue Res Section Body Doc Link PMC2977073 Disease Relevance 0 Pain Relevance 0

General Comments

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