INT342693

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.23
Pain Relevance 0.48

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (Prkaca, Gopc) cytoplasm (Prkaca, Gopc) plasma membrane (Prkaca, Gopc)
transport (Gopc) mitochondrion (Prkaca) protein complex (Prkaca)
Prkaca (Mus musculus)
Gopc (Mus musculus)
Pain Link Frequency Relevance Heat
Pain 8 92.00 High High
Nerve growth factor 1 87.64 High High
bradykinin 1 86.80 High High
adenocard 1 85.80 High High
Inflammation 1 82.92 Quite High
Sciatic nerve 4 75.44 Quite High
unmyelinated 4 74.36 Quite High
tetrodotoxin 3 58.88 Quite High
sodium channel 16 35.88 Quite Low
Lasting pain 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pain 12 92.00 High High
INFLAMMATION 1 82.92 Quite High
Targeted Disruption 5 55.88 Quite High
Infection 1 18.08 Low Low
Herpes Simplex Virus 1 15.84 Low Low
Nociception 4 5.00 Very Low Very Low Very Low
Neuropathic Pain 3 5.00 Very Low Very Low Very Low
Diabetic Neuropathy 1 5.00 Very Low Very Low Very Low
Nerve Compression Syndromes 1 5.00 Very Low Very Low Very Low
Injury 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
PKA phosphorylates serine residues within the intracellular loop I of NaV1.8 and alters its gating properties, shifting its steady-state activation curve to a more negative potential [8] (Fig. 4).
PKA Binding (alters) of Fig
1) Confidence 0.01 Published 2010 Journal Neuroscience Letters Section Body Doc Link PMC2977848 Disease Relevance 0.23 Pain Relevance 0.48

General Comments

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