INT342709

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Context Info
Confidence 0.12
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.29
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Mpz (Mus musculus)
Pain Link Frequency Relevance Heat
Locus ceruleus 3 68.44 Quite High
Catecholamine 1 64.48 Quite High
monoamine 5 6.56 Low Low
midbrain 26 5.00 Very Low Very Low Very Low
Glutamate 10 5.00 Very Low Very Low Very Low
Ventral tegmentum 7 5.00 Very Low Very Low Very Low
Inflammation 6 5.00 Very Low Very Low Very Low
Substantia nigra 3 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Drug Induced Neurotoxicity 1 99.72 Very High Very High Very High
Disease 88 73.56 Quite High
Death 5 61.44 Quite High
Parkinson's Disease 42 5.00 Very Low Very Low Very Low
Aging 15 5.00 Very Low Very Low Very Low
Stress 11 5.00 Very Low Very Low Very Low
INFLAMMATION 7 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 6 5.00 Very Low Very Low Very Low
Toxicity 5 5.00 Very Low Very Low Very Low
Dementia 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
On the one hand, neuromelanin can bind MPP+ (D'Amato et al., 1986) and paraquat (Lindquist et al., 1988), reducing their neurotoxicity, and accumulate dopaminergic drugs, regulating their intracellular concentration (Salazar et al., 1978).
Negative_regulation (reducing) of MPP Binding (bind) of associated with drug induced neurotoxicity
1) Confidence 0.12 Published 2010 Journal Frontiers in Neuroanatomy Section Body Doc Link PMC2978035 Disease Relevance 0.29 Pain Relevance 0.07

General Comments

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