INT342726

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Context Info
Confidence 0.03
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.64
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Park2) transport (Laptm5) Golgi apparatus (Park2)
endoplasmic reticulum (Park2) intracellular (Park2) protein complex (Park2)
Laptm5 (Mus musculus)
Park2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
midbrain 26 77.64 Quite High
Glutamate 10 5.00 Very Low Very Low Very Low
Ventral tegmentum 7 5.00 Very Low Very Low Very Low
Inflammation 6 5.00 Very Low Very Low Very Low
monoamine 5 5.00 Very Low Very Low Very Low
Locus ceruleus 3 5.00 Very Low Very Low Very Low
Substantia nigra 3 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
Neurotransmitter 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Parkinson's Disease 42 96.92 Very High Very High Very High
Disease 88 91.76 High High
Death 5 72.32 Quite High
Pressure And Volume Under Development 1 60.16 Quite High
Aging 15 5.00 Very Low Very Low Very Low
Stress 11 5.00 Very Low Very Low Very Low
INFLAMMATION 7 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 6 5.00 Very Low Very Low Very Low
Toxicity 5 5.00 Very Low Very Low Very Low
Dementia 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Parkin is a ubiquitously expressed protein, present in different subcellular fractions (Shimura et al., 1999), with several domains for protein–protein interactions and E3 ubiquitin protein ligase activity (Zhang et al., 2000).
E3 Binding (interactions) of Parkin
1) Confidence 0.03 Published 2010 Journal Frontiers in Neuroanatomy Section Body Doc Link PMC2978035 Disease Relevance 0.64 Pain Relevance 0.04

General Comments

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