INT34275

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Context Info
Confidence 0.31
First Reported 1987
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.24
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Ppp3ca) mitochondrion (Ppp3ca) nucleus (Ppp3ca)
enzyme binding (Ppp3ca) response to stress (Ppp3ca) cytoplasm (Ppp3ca)
Anatomy Link Frequency
GPI 1
Ppp3ca (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 3 98.40 Very High Very High Very High
opioid receptor 2 87.64 High High
MU agonist 1 75.00 Quite High
antagonist 1 75.00 Quite High
fibrosis 4 57.12 Quite High
anesthesia 1 22.84 Low Low
isoflurane 1 22.40 Low Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 3 95.44 Very High Very High Very High
Fibrosis 3 57.12 Quite High
Hypertrophy 2 10.80 Low Low
Arrhythmia Under Development 13 5.00 Very Low Very Low Very Low
Targeted Disruption 9 5.00 Very Low Very Low Very Low
Hyperplasia 5 5.00 Very Low Very Low Very Low
Sudden Death 4 5.00 Very Low Very Low Very Low
Death 3 5.00 Very Low Very Low Very Low
Heart Disease 2 5.00 Very Low Very Low Very Low
Heart Rate Under Development 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
-galactosidase, Cre, constitutively active CnA (?
Positive_regulation (active) of CnA
1) Confidence 0.31 Published 2010 Journal The Journal of Biological Chemistry Section Body Doc Link PMC2825466 Disease Relevance 0.24 Pain Relevance 0.03
Moreover, the corresponding epimer 2a behaved somewhat like that reported for alpha-CNA (1a) in that it possessed irreversible agonist activity in the GPI.
Positive_regulation (reported) of alpha-CNA in GPI associated with agonist
2) Confidence 0.06 Published 1987 Journal J. Med. Chem. Section Abstract Doc Link 3033246 Disease Relevance 0 Pain Relevance 0.24

General Comments

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