INT342781

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.97
Pain Relevance 0.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Prdm16) nucleus (Prdm16) intracellular (Prdm16)
DNA binding (Prdm16)
Anatomy Link Frequency
nerve 2
Prdm16 (Mus musculus)
Pain Link Frequency Relevance Heat
allodynia 10 92.08 High High
Neuropathic pain 6 78.16 Quite High
Dopamine 1 75.16 Quite High
agonist 2 49.92 Quite Low
intrathecal 1 48.28 Quite Low
Sciatic nerve 5 34.96 Quite Low
Neuropeptide 4 34.32 Quite Low
Peripheral nerve injury 1 32.56 Quite Low
Dorsal horn 3 31.36 Quite Low
Multiple sclerosis 1 20.12 Low Low
Disease Link Frequency Relevance Heat
Nervous System Injury 16 98.76 Very High Very High Very High
Neuropathic Pain 16 92.08 High High
Targeted Disruption 22 80.84 Quite High
Nociception 5 55.20 Quite High
Injury 2 36.36 Quite Low
Demyelinating Disease 1 20.12 Low Low
Cv Unclassified Under Development 1 18.76 Low Low
Stroke 1 18.08 Low Low
Disease 2 17.56 Low Low
Sprains And Strains 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To further define the role of galanin in the nervous system after nerve injury, we have used the tet-off system to develop a binary galanin overexpressing mouse line in which the overexpression can be suppressed by administration of the tetracycline analogue doxycycline (dox).
Negative_regulation (suppressed) of Gene_expression (overexpressing) of line in nerve associated with nervous system injury
1) Confidence 0.02 Published 2010 Journal Mol Pain Section Body Doc Link PMC2978139 Disease Relevance 0.97 Pain Relevance 0.34

General Comments

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