INT342783

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Context Info
Confidence 0.02
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.72
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Prdm16) extracellular region (Gal) Golgi apparatus (Gal)
nucleus (Prdm16) intracellular (Prdm16) DNA binding (Prdm16)
Anatomy Link Frequency
sciatic nerve 2
Prdm16 (Mus musculus)
Gal (Mus musculus)
Pain Link Frequency Relevance Heat
Sciatic nerve 5 99.28 Very High Very High Very High
allodynia 10 85.52 High High
nociceptor 1 77.44 Quite High
withdrawal 5 69.08 Quite High
Neuropathic pain 6 26.40 Quite Low
Neuropeptide 4 5.00 Very Low Very Low Very Low
Spinal cord 3 5.00 Very Low Very Low Very Low
Dorsal horn 3 5.00 Very Low Very Low Very Low
Central nervous system 2 5.00 Very Low Very Low Very Low
agonist 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 22 99.98 Very High Very High Very High
Nervous System Injury 16 98.96 Very High Very High Very High
Neuropathic Pain 16 85.52 High High
Nociception 5 50.00 Quite Low
Sprains And Strains 2 44.48 Quite Low
Disease 2 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low
Demyelinating Disease 1 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 1 5.00 Very Low Very Low Very Low
Urological Neuroanatomy 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These findings demonstrate that the double transgenic line overexpresses galanin in the DRG after sciatic nerve injury and that the overexpression is abolished by dox administration.
line Positive_regulation (overexpresses) of Gene_expression (overexpresses) of galanin in sciatic nerve associated with targeted disruption, nervous system injury and sciatic nerve
1) Confidence 0.02 Published 2010 Journal Mol Pain Section Body Doc Link PMC2978139 Disease Relevance 0.72 Pain Relevance 0.37

General Comments

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