INT34287

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Context Info
Confidence 0.10
First Reported 1987
Last Reported 2003
Negated 0
Speculated 1
Reported most in Abstract
Documents 3
Total Number 4
Disease Relevance 0.47
Pain Relevance 1.80

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Adarb1) mRNA processing (Adarb1) nucleolus (Adarb1)
RNA binding (Adarb1) nucleus (Adarb1) intracellular (Adarb1)
Anatomy Link Frequency
cortex 2
substantia gelatinosa 2
Adarb1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
adenocard 10 100.00 Very High Very High Very High
opioid receptor 4 100.00 Very High Very High Very High
Kappa opioid receptor 3 100.00 Very High Very High Very High
Enkephalin 1 100.00 Very High Very High Very High
Action potential 1 100.00 Very High Very High Very High
tetrodotoxin 1 99.16 Very High Very High Very High
substantia gelatinosa 8 98.76 Very High Very High Very High
IPN 2 94.52 High High
Spinal cord 4 94.00 High High
Glutamate receptor 1 88.16 High High
Disease Link Frequency Relevance Heat
Inflammatory Pain 2 94.52 High High
Pressure And Volume Under Development 7 88.80 High High
Depression 1 25.00 Low Low
Nociception 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These oscillations propagated uniformly at 0.5-1.5 mm/s over the cortex and were reversibly blocked by tetrodotoxin (TTX) and atropine, indicating that they depended on action potentials and activation of muscarinic receptors.
Regulation (depended) of Positive_regulation (activation) of receptors in cortex associated with action potential and tetrodotoxin
1) Confidence 0.10 Published 2003 Journal Cereb. Cortex Section Abstract Doc Link 12631570 Disease Relevance 0 Pain Relevance 0.35
Effects of specific activation of mu-, delta- and kappa-opioid receptors on the secretion of luteinizing hormone and prolactin in the ovariectomized rat.
Regulation (Effects) of Positive_regulation (activation) of receptors associated with kappa opioid receptor and enkephalin
2) Confidence 0.03 Published 1987 Journal Neuroendocrinology Section Title Doc Link 3033534 Disease Relevance 0 Pain Relevance 0.40
This study examined the effects of selective activation of kappa 1-opioid receptors on excitatory transmission in substantia gelatinosa (SG) using intracellular recordings from SG neurons in transverse slices of the young rat lumbar spinal cord.
Spec (examined) Regulation (effects) of Spec (examined) Positive_regulation (activation) of receptors in substantia gelatinosa associated with substantia gelatinosa, opioid receptor and spinal cord
3) Confidence 0.02 Published 1995 Journal J. Neurosci. Section Abstract Doc Link 7472439 Disease Relevance 0 Pain Relevance 0.52
The ability of DPCPX to block the effect of UP 202-56, in contrast to the lack of effect of DMPX, increased evidence for a predominant role of adenosine A1 receptors activation in the mechanism of action of UP 202-56.
Regulation (role) of Positive_regulation (activation) of receptors associated with adenocard
4) Confidence 0.01 Published 1998 Journal Pain Section Abstract Doc Link 9583764 Disease Relevance 0.47 Pain Relevance 0.54

General Comments

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