INT342872

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Context Info
Confidence 0.08
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.34
Pain Relevance 0.48

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Pth1r) plasma membrane (Pth1r) nucleus (Pth1r)
intracellular (Pth1r) cytoplasm (Pth1r) signal transducer activity (Pth1r)
Anatomy Link Frequency
vesicles 1
Pth1r (Mus musculus)
Pain Link Frequency Relevance Heat
depression 19 97.40 Very High Very High Very High
vagus nerve 138 95.68 Very High Very High Very High
Glutamate 2 93.96 High High
addiction 9 5.00 Very Low Very Low Very Low
Action potential 8 5.00 Very Low Very Low Very Low
medulla 6 5.00 Very Low Very Low Very Low
isoflurane 4 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
primary afferent fibers 3 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Depression 19 97.40 Very High Very High Very High
Disseminated Intravascular Coagulation 5 5.00 Very Low Very Low Very Low
Overdose 1 5.00 Very Low Very Low Very Low
Poisoning 1 5.00 Very Low Very Low Very Low
Sleep Disorders 1 5.00 Very Low Very Low Very Low
Sepsis 1 5.00 Very Low Very Low Very Low
Nociception 1 5.00 Very Low Very Low Very Low
Decapitation 1 5.00 Very Low Very Low Very Low
Injury 1 5.00 Very Low Very Low Very Low
Vomiting 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In accordance with previously published studies [26,37], the TS-dm-cNTS transmission consistently exhibited a small PPR for EPSC amplitude, which is likely to result from paired-pulse depression of the release probability from single terminals, indicating the number of glutamate-containing vesicles recruited for exocytosis is reduced during repeated stimulation.
Positive_regulation (exhibited) of PPR in vesicles associated with glutamate and depression
1) Confidence 0.08 Published 2010 Journal BMC Neurosci Section Body Doc Link PMC2978217 Disease Relevance 0.34 Pain Relevance 0.48

General Comments

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