INT342987

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.33
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.84
Pain Relevance 0.43

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (TRPV1, PTAFR) cytosol (TRPV1) transport (TRPV1)
nucleolus (PTAFR) nucleus (PTAFR) signal transducer activity (PTAFR)
Anatomy Link Frequency
immune cells 2
TRPV1 (Homo sapiens)
PTAFR (Homo sapiens)
Pain Link Frequency Relevance Heat
substance P 27 99.92 Very High Very High Very High
calcitonin gene related peptide 16 99.64 Very High Very High Very High
Inflammation 37 96.68 Very High Very High Very High
chemokine 9 83.36 Quite High
cytokine 9 67.28 Quite High
Inflammatory mediators 14 52.32 Quite High
antagonist 18 5.00 Very Low Very Low Very Low
qutenza 6 5.00 Very Low Very Low Very Low
tetrodotoxin 3 5.00 Very Low Very Low Very Low
TRP channel 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 48 96.68 Very High Very High Very High
Injury 5 96.00 Very High Very High Very High
Acid Reflux 3 92.08 High High
Esophageal Disease 22 91.16 High High
Gastroesophageal Reflux Disease 12 64.64 Quite High
Adhesions 1 32.44 Quite Low
Neurogenic Inflammation 2 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Ileitis 1 5.00 Very Low Very Low Very Low
Hyperplasia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We propose that acid in the lumen of the esophagus activates TRPV1 receptors causing the production and release of PAF, SP and CGRP that, in turn, may attract and activate immune cells contributing to inflammation and injury of the esophageal mucosa.
TRPV1 Positive_regulation (causing) of Localization (release) of PAF in immune cells associated with calcitonin gene related peptide, inflammation, injury and substance p
1) Confidence 0.33 Published 2010 Journal Journal of Neurogastroenterology and Motility Section Body Doc Link PMC2978390 Disease Relevance 0.84 Pain Relevance 0.43

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox