INT343013

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Context Info
Confidence 0.15
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 2.03
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (NOX5) oxidoreductase activity (NOX5) endoplasmic reticulum (NOX5)
Anatomy Link Frequency
muscle 2
NOX5 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 74 89.00 High High
cytokine 18 32.80 Quite Low
Inflammatory mediators 28 31.68 Quite Low
substance P 54 26.80 Quite Low
calcitonin gene related peptide 32 8.88 Low Low
chemokine 18 8.04 Low Low
antagonist 36 5.00 Very Low Very Low Very Low
qutenza 12 5.00 Very Low Very Low Very Low
tetrodotoxin 6 5.00 Very Low Very Low Very Low
TRP channel 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Esophageal Disease 44 99.68 Very High Very High Very High
INFLAMMATION 96 89.00 High High
Muscle Hypertonia 2 80.56 Quite High
Gastroesophageal Reflux Disease 24 22.08 Low Low
Injury 10 5.00 Very Low Very Low Very Low
Acid Reflux 6 5.00 Very Low Very Low Very Low
Neurogenic Inflammation 4 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low
Ileitis 2 5.00 Very Low Very Low Very Low
Hyperplasia 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Whereas NOX1-NOX5 are all present in esophageal circular muscle, only NOX5 mRNA was increased in the human specimen with esophagitis, as shown in Figure 18A.
Positive_regulation (increased) of NOX5 mRNA in muscle associated with esophageal disease
1) Confidence 0.15 Published 2010 Journal Journal of Neurogastroenterology and Motility Section Body Doc Link PMC2978390 Disease Relevance 1.02 Pain Relevance 0.10
Increased NOX5 mRNA in the esophagitis specimen was confirmed by real-time RT-PCR, when compared to normal human esophageal circular muscle, as shown in Figure 18B.
Positive_regulation (Increased) of NOX5 mRNA in muscle associated with esophageal disease
2) Confidence 0.10 Published 2010 Journal Journal of Neurogastroenterology and Motility Section Body Doc Link PMC2978390 Disease Relevance 1.02 Pain Relevance 0.10

General Comments

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