INT343134

Context Info Confidence 0.49 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.10 Pain Relevance 0.23

extracellular space (Cxcl1) extracellular region (Cxcl1)

Anatomy Link Frequency neurons 2 Cxcl1 (Rattus norvegicus)

Pain Link Frequency Relevance Heat Peripheral nervous system 3 71.60 Spinal cord 3 69.32 Central nervous system 3 64.64 parabrachial 8 50.00 Cholecystokinin 21 41.60 Serotonin 6 30.00 Pain 5 7.20 medulla 11 5.00 nociceptor 7 5.00 alcohol 3 5.00

Disease Link Frequency Relevance Heat Repression 1 98.20 Hyperphagia 1 13.12 Obesity 1 11.84 Pain 5 7.20 Hypersensitivity 6 5.00 Nociception 3 5.00 Targeted Disruption 2 5.00 INFLAMMATION 2 5.00 Anorexia 1 5.00 Headache 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Furthermore, the expression of TLE1 and TLE4 in the Runx1-expressing neurons of the LPBS may indicate that the role of Runx1 in these cells may, at least in part, be mediated through the recruitment of Gro/TLE proteins and consequent transcriptional repression, although this possibility remains to be verified.

Positive_regulation (mediated) of Gro Binding (recruitment) of in neurons associated with repression

1) Confidence 0.49 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2978708 Disease Relevance 0.10 Pain Relevance 0.23

General Comments

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