INT343163

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Context Info
Confidence 0.08
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.50
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (ACSL4, PTGS2) endoplasmic reticulum (ACSL4, PTGS2) mitochondrion (ACSL4)
peroxisome (ACSL4) enzyme binding (PTGS2) protein complex (PTGS2)
Anatomy Link Frequency
MDA-MB-231 2
ACSL4 (Homo sapiens)
PTGS2 (Homo sapiens)
Pain Link Frequency Relevance Heat
COX2 1 5.00 Very Low Very Low Very Low
COX-2 inhibitor 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Breast Cancer 37 98.40 Very High Very High Very High
Hepatocellular Cancer 5 84.56 Quite High
Aggression 6 72.24 Quite High
Cancer 14 25.00 Low Low
Injury 21 5.00 Very Low Very Low Very Low
Apoptosis 12 5.00 Very Low Very Low Very Low
Colon Cancer 9 5.00 Very Low Very Low Very Low
Targeted Disruption 4 5.00 Very Low Very Low Very Low
Wound Healing 3 5.00 Very Low Very Low Very Low
Metastasis 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The first novel finding is that ACSL4 regulates the expression of cyclooxygenase-2 (COX-2) and the production of prostaglandin in MDA-MB-231 cells.
ACSL4 Regulation (regulates) of Gene_expression (expression) of cyclooxygenase-2 in MDA-MB-231
1) Confidence 0.08 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2978721 Disease Relevance 0.50 Pain Relevance 0

General Comments

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