INT343164

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.08
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (ACSL4) small molecule metabolic process (ACSL4) endoplasmic reticulum (ACSL4)
peroxisome (ACSL4) lipid metabolic process (ALOX15) cytoplasm (ALOX15)
ACSL4 (Homo sapiens)
ALOX15 (Homo sapiens)
Pain Link Frequency Relevance Heat
COX2 1 54.28 Quite High
cINOD 1 17.20 Low Low
COX-2 inhibitor 1 6.80 Low Low
Disease Link Frequency Relevance Heat
Metastasis 2 98.96 Very High Very High Very High
Cancer 14 98.32 Very High Very High Very High
Apoptosis 12 96.48 Very High Very High Very High
Noninfiltrating Intraductal Carcinoma 1 87.80 High High
Carcinoma 1 86.76 High High
Breast Cancer 37 82.48 Quite High
Colon Cancer 9 22.88 Low Low
INFLAMMATION 1 16.80 Low Low
Injury 21 5.00 Very Low Very Low Very Low
Aggression 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Since ACSL4 controls the expression of COX-2 through the induction of lipooxygenase metabolites of AA, as stated above, the functional interaction of COX-2 and LOX enzymes could have therapeutic implications.
ACSL4 Regulation (controls) of Positive_regulation (induction) of lipooxygenase
1) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2978721 Disease Relevance 1.08 Pain Relevance 0.03

General Comments

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