INT343189

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.59
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 1.49
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (ACSL4) small molecule metabolic process (ACSL4) endoplasmic reticulum (ACSL4)
peroxisome (ACSL4) ligase activity (ACSL4)
Anatomy Link Frequency
liver 3
colon 1
ACSL4 (Homo sapiens)
Pain Link Frequency Relevance Heat
COX2 4 5.00 Very Low Very Low Very Low
COX-2 inhibitor 4 5.00 Very Low Very Low Very Low
cINOD 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Aggression 24 99.68 Very High Very High Very High
Breast Cancer 148 97.06 Very High Very High Very High
Liver Cancer 4 96.52 Very High Very High Very High
Repression 4 90.48 High High
Cancer 56 85.48 High High
Colon Cancer 36 72.96 Quite High
Apoptosis 48 67.68 Quite High
Metastasis 8 47.84 Quite Low
Hyperplasia 4 36.24 Quite Low
Advanced Or Metastatic Breast Cancer 4 34.48 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
After several weeks, colonies in which the expressed ACSL4 was regulated by tetracycline (2 µg/ml) were selected, cultured and subjected to different functional assays.
Regulation (regulated) of Gene_expression (expressed) of ACSL4
1) Confidence 0.59 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2978721 Disease Relevance 0.09 Pain Relevance 0
As for ACSL4, altered TSPO expression has also been involved in several pathological conditions including breast, colon and liver cancer [18], [19].
Regulation (altered) of Gene_expression (expression) of ACSL4 in liver associated with liver cancer
2) Confidence 0.26 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2978721 Disease Relevance 0.37 Pain Relevance 0
A breast cancer cell model comprising different cell lines with varying cell proliferation, invasive and metastatic behavior was used to investigate the possible effect of the differential expression of ACSL4 on the aggression phenotype.
Spec (possible) Regulation (effect) of Gene_expression (expression) of ACSL4 associated with aggression and breast cancer
3) Confidence 0.26 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2978721 Disease Relevance 0.66 Pain Relevance 0
As for ACSL4, altered TSPO expression has also been involved in several pathological conditions including breast, colon and liver cancer [18], [19].
Regulation (altered) of in colon Gene_expression (expression) of ACSL4 in liver associated with liver cancer
4) Confidence 0.09 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2978721 Disease Relevance 0.37 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox