INT343485

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Context Info
Confidence 0.25
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.51
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Epo, VEGFA) extracellular region (Epo, VEGFA) growth (VEGFA)
proteinaceous extracellular matrix (VEGFA) cytoplasm (VEGFA)
Anatomy Link Frequency
endothelial cells 2
Epo (Mus musculus)
VEGFA (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 6 64.16 Quite High
Inflammatory response 22 5.00 Very Low Very Low Very Low
fibrosis 8 5.00 Very Low Very Low Very Low
Inflammation 8 5.00 Very Low Very Low Very Low
cytokine 6 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
cva 4 5.00 Very Low Very Low Very Low
Analgesic 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
lidocaine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 68 88.08 High High
Injury 4 86.08 High High
Diabetes Mellitus 2 85.28 High High
Obesity 54 81.72 Quite High
Aging 2 50.96 Quite High
Death 2 23.28 Low Low
INFLAMMATION 30 5.00 Very Low Very Low Very Low
Fibrosis 8 5.00 Very Low Very Low Very Low
Cyst 8 5.00 Very Low Very Low Very Low
Hemorrhage 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Nakano and colleagues demonstrated that EPO treatment increases VEGF expression and promotes angiogenesis in peripheral ischemic tissues in mice [10].
EPO Positive_regulation (increases) of Gene_expression (expression) of VEGF
1) Confidence 0.25 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2981551 Disease Relevance 0.32 Pain Relevance 0.03
Wang et al. demonstrated that EPO can promote angiogenesis by stimulating VEGF secretion from neural progenitor cells and VEGF-receptor expression in cerebral endothelial cells [13].
EPO Positive_regulation (stimulating) of Gene_expression (expression) of VEGF in endothelial cells
2) Confidence 0.25 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2981551 Disease Relevance 0.19 Pain Relevance 0.06

General Comments

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