INT343538

Context Info Confidence 0.08 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.20 Pain Relevance 0.05

cytoplasm (TGFB1, GLI2) nucleus (TGFB1, GLI2) cell differentiation (GLI2) aging (TGFB1) intracellular (GLI2) cilium (GLI2)

TGFB1 (Homo sapiens) GLI2 (Homo sapiens)

Pain Link Frequency Relevance Heat Mechanotransduction 8 95.36 metalloproteinase 1 5.00 Pain 1 5.00

Disease Link Frequency Relevance Heat Cancer 46 76.16 Advanced Or Metastatic Breast Cancer 1 50.00 Metastasis 23 5.00 Breast Cancer 6 5.00 Bone Cancer 6 5.00 Hypercalcemia 5 5.00 Osteolysis 3 5.00 Pressure And Volume Under Development 3 5.00 Adhesions 2 5.00 Osteoporosis 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

We found that blebbistatin blocked the ability of TGF-ß to stimulate Gli2 and PTHrP expression.

TGF Positive_regulation (stimulate) of Gene_expression (expression) of Gli2

1) Confidence 0.08 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2981576 Disease Relevance 0.20 Pain Relevance 0.05

General Comments

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