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Context Info
Confidence 0.07
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.65
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (GLI2, ROCK1) cell differentiation (GLI2) Golgi apparatus (ROCK1)
intracellular (GLI2) cilium (GLI2) cell proliferation (GLI2)
GLI2 (Homo sapiens)
ROCK1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Mechanotransduction 8 64.36 Quite High
metalloproteinase 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Metastasis 23 99.24 Very High Very High Very High
Osteolysis 3 88.88 High High
Cancer 46 85.08 High High
Hypertension 1 78.56 Quite High
Heart Disease 1 73.20 Quite High
Breast Cancer 6 59.32 Quite High
Advanced Or Metastatic Breast Cancer 1 50.00 Quite Low
Stress 2 22.24 Low Low
Bone Cancer 6 5.00 Very Low Very Low Very Low
Hypercalcemia 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Thus Gli2 may be a potentially more useful target than ROCK for treating bone metastases in the clinic.
Gli2 Binding (target) of ROCK associated with metastasis
1) Confidence 0.07 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2981576 Disease Relevance 0.65 Pain Relevance 0.03

General Comments

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