INT343638

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Grm1) plasma membrane (Grm1) nucleus (Grm1)
signal transducer activity (Grm1)
Adp (Mus musculus)
Grm1 (Mus musculus)
Pain Link Frequency Relevance Heat
Glutamate 7 50.00 Quite Low
Pyramidal cell 15 39.44 Quite Low
Action potential 22 5.00 Very Low Very Low Very Low
Calcium channel 14 5.00 Very Low Very Low Very Low
addiction 8 5.00 Very Low Very Low Very Low
Glutamate receptor 6 5.00 Very Low Very Low Very Low
antagonist 4 5.00 Very Low Very Low Very Low
Hippocampus 4 5.00 Very Low Very Low Very Low
Neuronal excitability 3 5.00 Very Low Very Low Very Low
conotoxin 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 7 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Sprains And Strains 1 5.00 Very Low Very Low Very Low
Intellectual Impairment 1 5.00 Very Low Very Low Very Low
Neurological Disease 1 5.00 Very Low Very Low Very Low
Epilepsy 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Indeed, the pharmacology suggests that the medium ADP requires activation of mGluR5 (and to a lesser extent mGluR1) and activation of G proteins (likely Gq) and PLC.
ADP Positive_regulation (requires) of Positive_regulation (activation) of mGluR1
1) Confidence 0.00 Published 2010 Journal PLoS Biology Section Body Doc Link PMC2982802 Disease Relevance 0 Pain Relevance 0

General Comments

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