INT343719

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Context Info
Confidence 0.00
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 4
Disease Relevance 1.90
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (PAH) small molecule metabolic process (PAH) cell death (Nlrp1a)
nucleus (Nlrp1a) enzyme binding (Nlrp1a) cellular nitrogen compound metabolic process (PAH)
Nlrp1a (Mus musculus)
PAH (Homo sapiens)
Pain Link Frequency Relevance Heat
alcohol 12 70.16 Quite High
Inflammation 12 5.00 Very Low Very Low Very Low
ketamine 4 5.00 Very Low Very Low Very Low
anesthesia 4 5.00 Very Low Very Low Very Low
fibrosis 4 5.00 Very Low Very Low Very Low
Immobilon 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypertension 108 100.00 Very High Very High Very High
Hypoxia 60 96.88 Very High Very High Very High
Pulmonary Disease 20 82.32 Quite High
Targeted Disruption 12 75.08 Quite High
Sepsis 8 73.72 Quite High
Disease 20 70.84 Quite High
Stress 28 50.28 Quite High
INFLAMMATION 12 5.00 Very Low Very Low Very Low
Asthma 8 5.00 Very Low Very Low Very Low
Cardiomegaly 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, the resulting increase in GSNO-R activity correlates with protection from NAC-induced PH.
NAC Positive_regulation (induced) of PH associated with hypertension
1) Confidence 0.00 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2982841 Disease Relevance 0.54 Pain Relevance 0.04
Gender differences in GSNO-R activity appear to explain the difference in the ability of NAC to induce PH: female and castrated male animals are protected from NAC-induced PH.
NAC Positive_regulation (induced) of PH associated with hypertension
2) Confidence 0.00 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2982841 Disease Relevance 0.35 Pain Relevance 0
To determine if the female gender is less susceptible to NAC-induced PH, C57BL6/129SvEv mice were subjected to normoxia, 10 mg/ml NAC, 1 mg/ml SNOAC, or hypoxia for a period of three weeks [11].
NAC Positive_regulation (induced) of PH associated with hypoxia and hypertension
3) Confidence 0.00 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2982841 Disease Relevance 0.56 Pain Relevance 0
Gender differences in GSNO-R activity appear to explain the difference in the ability of NAC to induce PH: female and castrated male animals are protected from NAC-induced PH.
NAC Positive_regulation (induce) of PH associated with hypertension
4) Confidence 0.00 Published 2010 Journal PLoS ONE Section Abstract Doc Link PMC2982841 Disease Relevance 0.45 Pain Relevance 0

General Comments

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