INT343806

Context Info Confidence 0.57 First Reported 2010 Last Reported 2010 Negated 0 Speculated 0 Reported most in Body Documents 3 Total Number 6 Disease Relevance 2.54 Pain Relevance 1.18

cytosol (CORO7) Golgi apparatus (CORO7) cytoplasmic membrane-bounded vesicle (CORO7) cytoplasm (CORO7)

Anatomy Link Frequency T cells 3 blood 2 NK cells 1 CORO7 (Homo sapiens)

Pain Link Frequency Relevance Heat depression 4 98.60 anesthesia 12 90.24 epidural 2 89.80 Inflammatory response 14 76.48 addiction 24 73.84 Inflammation 28 5.00 cytokine 6 5.00 palliative 4 5.00 fibrosis 4 5.00 iatrogenic 2 5.00

Disease Link Frequency Relevance Heat Depression 4 98.60 Systemic Inflammatory Response Syndrome 44 82.64 Injury 22 81.48 Colon Cancer 80 76.88 INFLAMMATION 34 76.08 Malignant Neoplastic Disease 28 73.52 Stomach Cancer 4 68.56 Adult Respiratory Distress Syndrome 40 63.60 Pressure Volume 2 Under Development 16 58.16 Cancer 76 57.04

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Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

On POD 4, the count of lymphocytes, CD4+T cells and CD8+T cells were significantly higher in LCR group than OCR group.

Gene_expression (group) of POD in T cells

1) Confidence 0.57 Published 2010 Journal BMC Gastroenterol Section Body Doc Link PMC2988071 Disease Relevance 0.25 Pain Relevance 0.04

The counts of CD4+T cells, CD8+T cells, CD45RO+T cells and NK cells were more in LCR group than OCR group, especially on POD 4.

Gene_expression (group) of POD in NK cells

2) Confidence 0.57 Published 2010 Journal BMC Gastroenterol Section Body Doc Link PMC2988071 Disease Relevance 0.58 Pain Relevance 0.04

On POD 7, the count of CD4+T cells, CD8+T cells and CD45RO+T cells rose to the preoperative levels in LCR group.

Gene_expression (rose) of POD in T cells

3) Confidence 0.49 Published 2010 Journal BMC Gastroenterol Section Body Doc Link PMC2988071 Disease Relevance 0.42 Pain Relevance 0.05

The counts of CD4+T cells, CD8+T cells, CD45RO+T cells and NK cells were more in LCR group than OCR group, especially on POD 4.

Gene_expression (group) of POD in T cells

4) Confidence 0.19 Published 2010 Journal BMC Gastroenterol Section Body Doc Link PMC2988071 Disease Relevance 0.58 Pain Relevance 0.04

Serum from whole blood was obtained intraoperatively and on POD 1, POD 3, POD 5 and POD 14.

Gene_expression (on) of POD in blood

5) Confidence 0.08 Published 2010 Journal J Transl Med Section Body Doc Link PMC2984412 Disease Relevance 0.36 Pain Relevance 0.50

Serum from whole blood was obtained intraoperatively and on POD 1, POD 3, POD 5 and POD 14.

Gene_expression (on) of POD in blood

6) Confidence 0.08 Published 2010 Journal J Transl Med Section Body Doc Link PMC2984412 Disease Relevance 0.36 Pain Relevance 0.50

General Comments

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