INT343831

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Context Info
Confidence 0.11
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.19
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (TICAM1, TLR4) plasma membrane (TICAM1, TLR4) cytosol (TICAM1)
intracellular (TLR4) cytoplasm (TLR4) signal transducer activity (TICAM1)
TICAM1 (Homo sapiens)
TLR4 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 5 90.20 High High
cytokine 47 37.72 Quite Low
Inflammation 66 37.32 Quite Low
agonist 54 5.00 Very Low Very Low Very Low
fibrosis 18 5.00 Very Low Very Low Very Low
Inflammatory response 15 5.00 Very Low Very Low Very Low
chemokine 10 5.00 Very Low Very Low Very Low
tolerance 7 5.00 Very Low Very Low Very Low
Bile 5 5.00 Very Low Very Low Very Low
alcohol 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cirrhosis 61 73.80 Quite High
Fibrosis 24 63.76 Quite High
Injury 31 50.00 Quite Low
Stress 9 44.36 Quite Low
Viral Infection 2 39.04 Quite Low
INFLAMMATION 80 37.32 Quite Low
Apoptosis 13 5.00 Very Low Very Low Very Low
Infection 12 5.00 Very Low Very Low Very Low
Reperfusion Injury 11 5.00 Very Low Very Low Very Low
Hepatitis C Virus Infection 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The MyD88-independent TRIF-dependent TLR4 pathway activates IRF3, and induces the expression of IFN-?
TRIF Positive_regulation (activates) of Gene_expression (pathway) of TLR4
1) Confidence 0.11 Published 2010 Journal Fibrogenesis Tissue Repair Section Body Doc Link PMC2984459 Disease Relevance 0.19 Pain Relevance 0.19

General Comments

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