INT343832

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Context Info
Confidence 0.11
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.43
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (EDA, TLR4) plasma membrane (EDA, TLR4) pigmentation (EDA)
cell differentiation (EDA) extracellular region (EDA) intracellular (TLR4)
Anatomy Link Frequency
MD2 2
EDA (Homo sapiens)
TLR4 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 47 93.60 High High
Inflammation 66 84.72 Quite High
chemokine 10 54.88 Quite High
Inflammatory response 15 50.84 Quite High
agonist 54 5.00 Very Low Very Low Very Low
fibrosis 18 5.00 Very Low Very Low Very Low
tolerance 7 5.00 Very Low Very Low Very Low
Bile 5 5.00 Very Low Very Low Very Low
metalloproteinase 5 5.00 Very Low Very Low Very Low
alcohol 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 80 84.72 Quite High
Pathologic Processes 1 82.44 Quite High
Injury 31 76.88 Quite High
Edema 1 44.20 Quite Low
Sepsis 5 23.16 Low Low
Hepatotoxicity 3 22.20 Low Low
Shock 2 19.04 Low Low
Cirrhosis 61 5.00 Very Low Very Low Very Low
Fibrosis 24 5.00 Very Low Very Low Very Low
Apoptosis 13 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
EDA stimulation of TLR4 is dependent upon co-expression of MD2, a TLR4 accessory protein [48].


Positive_regulation (dependent) of EDA Positive_regulation (stimulation) of TLR4 in MD2
1) Confidence 0.11 Published 2010 Journal Fibrogenesis Tissue Repair Section Body Doc Link PMC2984459 Disease Relevance 0.43 Pain Relevance 0.27

General Comments

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