INT343847

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.11
Pain Relevance 0.87

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (IRF6, TBCE) protein folding (TBCE) cytosol (IRF6)
cytoskeleton (TBCE) nucleus (IRF6) DNA binding (IRF6)
Anatomy Link Frequency
leukocyte 1
IRF6 (Homo sapiens)
TBCE (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 54 100.00 Very High Very High Very High
chemokine 10 98.32 Very High Very High Very High
cytokine 47 97.76 Very High Very High Very High
Inflammation 66 91.88 High High
Inflammatory response 15 88.52 High High
Inflammatory mediators 3 79.64 Quite High
tolerance 7 67.76 Quite High
ischemia 4 53.76 Quite High
Bile 5 42.28 Quite Low
fibrosis 18 19.60 Low Low
Disease Link Frequency Relevance Heat
INFLAMMATION 80 91.88 High High
Infection 12 69.28 Quite High
Hepatitis C Virus Infection 10 68.88 Quite High
Hepatitis 5 62.32 Quite High
Targeted Disruption 1 60.32 Quite High
Cirrhosis 61 54.80 Quite High
Reperfusion Injury 11 54.72 Quite High
Cv Unclassified Under Development 3 53.76 Quite High
Stress 9 51.44 Quite High
Injury 31 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
LPS stimulates TLR4 on KCs to enhance hepatocyte damage, increase leukocyte infiltration and secrete pro-fibrogenic cytokines.
LPS Positive_regulation (stimulates) of KCs in leukocyte associated with agonist and cytokine
1) Confidence 0.01 Published 2010 Journal Fibrogenesis Tissue Repair Section Body Doc Link PMC2984459 Disease Relevance 1.11 Pain Relevance 0.87

General Comments

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