INT343859

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.10
Pain Relevance 0.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (IRF6, TBCE) protein folding (TBCE) cytosol (IRF6)
cytoskeleton (TBCE) nucleus (IRF6) DNA binding (IRF6)
Anatomy Link Frequency
liver 1
IRF6 (Homo sapiens)
TBCE (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 54 100.00 Very High Very High Very High
cytokine 47 99.00 Very High Very High Very High
alcohol 4 96.88 Very High Very High Very High
Inflammation 66 87.40 High High
Bile 5 64.48 Quite High
Inflammatory response 15 61.56 Quite High
ischemia 4 12.08 Low Low
fibrosis 18 5.00 Very Low Very Low Very Low
chemokine 10 5.00 Very Low Very Low Very Low
tolerance 7 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 31 96.08 Very High Very High Very High
INFLAMMATION 80 87.40 High High
Hepatotoxicity 3 84.12 Quite High
Endotoxemia 2 81.84 Quite High
Alcoholic Liver Diseases 2 81.32 Quite High
Liver Disease 6 69.76 Quite High
Fatty Liver 3 68.44 Quite High
Biliary Liver Cirrhosis 4 68.32 Quite High
Obesity 7 55.00 Quite High
Hepatitis 5 51.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Binding of LPS to CD14/TLR4 on KCs activates production of cytokines and oxidants, primary mediators of early ethanol-induced liver injury.
LPS Binding (Binding) of KCs in liver associated with injury, agonist and cytokine
1) Confidence 0.01 Published 2010 Journal Fibrogenesis Tissue Repair Section Body Doc Link PMC2984459 Disease Relevance 1.10 Pain Relevance 0.51

General Comments

This test has worked.

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