INT34393

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Context Info
Confidence 0.36
First Reported 1987
Last Reported 1987
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 1.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Oprd1, Adcy1) nucleus (Adcy1) cytoplasm (Oprd1)
signal transducer activity (Oprd1)
Oprd1 (Rattus norvegicus)
Adcy1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
opioid receptor 2 100.00 Very High Very High Very High
dopamine receptor 4 99.76 Very High Very High Very High
Delta opioid receptors 4 96.24 Very High Very High Very High
narcan 3 95.52 Very High Very High Very High
Morphine 5 93.76 High High
Opioid 2 90.48 High High
adenocard 2 89.20 High High
Dopamine 2 75.00 Quite High
Enkephalin 2 62.44 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These data show that D-1 dopamine receptor-stimulated adenylate cyclase activity in rat neostriatum, but not that stimulated through other receptors, is inhibited by two pharmacologically distinct opioid receptor subtypes.
opioid receptor Negative_regulation (inhibited) of adenylate cyclase associated with dopamine receptor and opioid receptor
1) Confidence 0.36 Published 1987 Journal Naunyn Schmiedebergs Arch. Pharmacol. Section Abstract Doc Link 3035383 Disease Relevance 0 Pain Relevance 1.27

General Comments

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