INT343974

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Context Info
Confidence 0.31
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.09
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (SNCA) oxidoreductase activity (SNCA) cell death (SNCA)
extracellular region (SNCA) histone binding (SNCA) plasma membrane (SNCA)
SNCA (Homo sapiens)
SNCA - A53T (1)
Pain Link Frequency Relevance Heat
Substantia nigra 55 90.44 High High
Dopamine 19 73.08 Quite High
midbrain 1 13.28 Low Low
anesthesia 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 2 87.80 High High
Disease 32 5.00 Very Low Very Low Very Low
Toxicity 13 5.00 Very Low Very Low Very Low
Parkinson's Disease 9 5.00 Very Low Very Low Very Low
Targeted Disruption 3 5.00 Very Low Very Low Very Low
Cytomegalovirus Infection 3 5.00 Very Low Very Low Very Low
Respiratory Tract Infection 2 5.00 Very Low Very Low Very Low
Exsanguination 1 5.00 Very Low Very Low Very Low
Overdose 1 5.00 Very Low Very Low Very Low
Epilepsy 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Delivery with AAV1/2-A53T alpha-synuclein produced a 42% and a 29% decrease in NeuN-immunoreactive cells compared to AAV1/2-empty vector (P < 0.01) and AAV1/2-GFP (P < 0.01) treated groups respectively.
Negative_regulation (decrease) of Gene_expression (produced) of A53T alpha-synuclein (A53T)
1) Confidence 0.31 Published 2010 Journal Mol Neurodegener Section Body Doc Link PMC2984491 Disease Relevance 0.09 Pain Relevance 0.16

General Comments

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