INT343991

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Context Info
Confidence 0.17
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 4.42
Pain Relevance 1.93

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (UQCRC2) mitochondrion (UQCRC2) small molecule metabolic process (UQCRC2)
Anatomy Link Frequency
cerebellum 6
hippocampus 2
UQCRC2 (Homo sapiens)
Pain Link Frequency Relevance Heat
ischemia 256 99.68 Very High Very High Very High
Hippocampus 164 99.48 Very High Very High Very High
adenocard 4 48.96 Quite Low
Inflammation 12 5.00 Very Low Very Low Very Low
tolerance 8 5.00 Very Low Very Low Very Low
aspirin 4 5.00 Very Low Very Low Very Low
Buprenorphine 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cv Unclassified Under Development 232 99.68 Very High Very High Very High
Stroke 228 98.52 Very High Very High Very High
Apoptosis 80 91.36 High High
Death 140 81.92 Quite High
Hypertension 92 50.00 Quite Low
Pressure And Volume Under Development 12 43.48 Quite Low
Disease 4 39.88 Quite Low
Cv General 4 Under Development 20 5.00 Very Low Very Low Very Low
Stress 12 5.00 Very Low Very Low Very Low
INFLAMMATION 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Cytochrome b-c1 complex subunit 2 (QCR2) was down-regulated in both the hippocampus and cerebellum.
Negative_regulation (down) of Negative_regulation (regulated) of QCR2 in cerebellum associated with hippocampus
1) Confidence 0.17 Published 2010 Journal Chin Med Section Body Doc Link PMC2984508 Disease Relevance 0.85 Pain Relevance 0.51
As to the possible mechanisms of PZH protective effects on ischemia and stroke, proteomic results indicated that the cytochrome b-c1 complex subunit 2 (QCR2) was down-regulated in the ischemia with PZH treatment group in both the hippocampus and cerebellum as compared to the ischemia control group (Tables 5 and 6).
Negative_regulation (down) of Negative_regulation (regulated) of QCR2 in cerebellum associated with stroke, ischemia and hippocampus
2) Confidence 0.17 Published 2010 Journal Chin Med Section Body Doc Link PMC2984508 Disease Relevance 1.36 Pain Relevance 0.46
Cytochrome b-c1 complex subunit 2 (QCR2) was down-regulated in both the hippocampus and cerebellum.
Negative_regulation (down) of in hippocampus Negative_regulation (regulated) of QCR2 in cerebellum associated with hippocampus
3) Confidence 0.06 Published 2010 Journal Chin Med Section Body Doc Link PMC2984508 Disease Relevance 0.85 Pain Relevance 0.51
As to the possible mechanisms of PZH protective effects on ischemia and stroke, proteomic results indicated that the cytochrome b-c1 complex subunit 2 (QCR2) was down-regulated in the ischemia with PZH treatment group in both the hippocampus and cerebellum as compared to the ischemia control group (Tables 5 and 6).
Negative_regulation (down) of in hippocampus Negative_regulation (regulated) of QCR2 in cerebellum associated with stroke, ischemia and hippocampus
4) Confidence 0.06 Published 2010 Journal Chin Med Section Body Doc Link PMC2984508 Disease Relevance 1.36 Pain Relevance 0.46

General Comments

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