INT344086

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Context Info
Confidence 0.36
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.06
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Drd5) plasma membrane (Drd5) signal transducer activity (Drd5)
Drd5 (Mus musculus)
Pain Link Frequency Relevance Heat
Dopamine 103 99.62 Very High Very High Very High
agonist 24 95.48 Very High Very High Very High
dopamine receptor 29 72.00 Quite High
gABA 24 48.84 Quite Low
antagonist 11 42.64 Quite Low
GABAergic 18 5.00 Very Low Very Low Very Low
Thalamus 7 5.00 Very Low Very Low Very Low
Substantia nigra 6 5.00 Very Low Very Low Very Low
positron emission tomography 4 5.00 Very Low Very Low Very Low
Glutamate 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Movement Disorders 2 55.92 Quite High
Catalepsy 1 41.04 Quite Low
Disease 22 5.00 Very Low Very Low Very Low
Parkinson's Disease 21 5.00 Very Low Very Low Very Low
Attention Deficit Hyperactivity Disorder 3 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Congenital Anomalies 2 5.00 Very Low Very Low Very Low
Urological Neuroanatomy 2 5.00 Very Low Very Low Very Low
Tourette's Syndrome 1 5.00 Very Low Very Low Very Low
Fatigue 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For example, dopamine binds with higher affinity to D3-, D4-, and D5-receptors than to D1-receptors (Sunahara et al., 1991; Missale et al., 1998), and SKF38393 is a partial rather than full agonist at D1LRs (Twery et al., 1994; Kreiss et al., 1996; Gleason and Witkin, 2004), complicating the interpretation of some of the earlier studies.


D5-receptor Binding (affinity) of associated with dopamine and agonist
1) Confidence 0.36 Published 2010 Journal Frontiers in Neuroanatomy Section Body Doc Link PMC2987554 Disease Relevance 0.06 Pain Relevance 0.37

General Comments

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