INT344101

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 0.84

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Abat) endoplasmic reticulum (Drd1a) plasma membrane (Drd1a)
nucleus (Drd1a) intracellular (Drd1a) signal transducer activity (Drd1a)
Anatomy Link Frequency
neurons 3
Drd1a (Rattus norvegicus)
Abat (Rattus norvegicus)
Pain Link Frequency Relevance Heat
gABA 48 100.00 Very High Very High Very High
GABAergic 36 93.68 High High
Dopamine 206 92.28 High High
agonist 48 91.20 High High
dopamine receptor 58 81.12 Quite High
Glutamate 8 54.32 Quite High
antagonist 22 49.84 Quite Low
tetrodotoxin 4 12.80 Low Low
sodium channel 4 11.96 Low Low
Thalamus 14 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 44 5.00 Very Low Very Low Very Low
Parkinson's Disease 42 5.00 Very Low Very Low Very Low
Attention Deficit Hyperactivity Disorder 6 5.00 Very Low Very Low Very Low
Targeted Disruption 4 5.00 Very Low Very Low Very Low
Congenital Anomalies 4 5.00 Very Low Very Low Very Low
Urological Neuroanatomy 4 5.00 Very Low Very Low Very Low
Movement Disorders 4 5.00 Very Low Very Low Very Low
Tourette's Syndrome 2 5.00 Very Low Very Low Very Low
Fatigue 2 5.00 Very Low Very Low Very Low
Anxiety Disorder 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Not all studies have agreed that the activation of D1LRs increases GABA release and reduces the activity of neurons in the SNr.
Positive_regulation (activation) of D1LRs in neurons Positive_regulation (increases) of Localization (release) of GABA in neurons associated with gaba
1) Confidence 0.01 Published 2010 Journal Frontiers in Neuroanatomy Section Body Doc Link PMC2987554 Disease Relevance 0 Pain Relevance 0.38
Microdialysis studies showed that activation of D2LRs decreased GABA release in the rat GP while activation of D1LRs increased GABA release (Floran et al., 1990, 1997).
Positive_regulation (activation) of D1LRs Positive_regulation (increased) of Localization (release) of GABA associated with gaba
2) Confidence 0.01 Published 2010 Journal Frontiers in Neuroanatomy Section Body Doc Link PMC2987554 Disease Relevance 0 Pain Relevance 0.46

General Comments

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