INT344109

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Context Info
Confidence 0.18
First Reported 2010
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

isomerase activity (Gpi) carbohydrate metabolic process (Gpi) cytoplasm (Gpi)
cytosol (Gpi) extracellular space (Gpi) extracellular region (Gpi)
Gpi (Rattus norvegicus)
Pain Link Frequency Relevance Heat
gABA 24 97.92 Very High Very High Very High
dopamine receptor 29 87.28 High High
Glutamate 4 84.80 Quite High
Dopamine 103 74.40 Quite High
agonist 24 5.00 Very Low Very Low Very Low
GABAergic 18 5.00 Very Low Very Low Very Low
antagonist 11 5.00 Very Low Very Low Very Low
Thalamus 7 5.00 Very Low Very Low Very Low
Substantia nigra 6 5.00 Very Low Very Low Very Low
positron emission tomography 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 22 22.24 Low Low
Parkinson's Disease 21 13.12 Low Low
Attention Deficit Hyperactivity Disorder 3 10.76 Low Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Congenital Anomalies 2 5.00 Very Low Very Low Very Low
Urological Neuroanatomy 2 5.00 Very Low Very Low Very Low
Movement Disorders 2 5.00 Very Low Very Low Very Low
Tourette's Syndrome 1 5.00 Very Low Very Low Very Low
Fatigue 1 5.00 Very Low Very Low Very Low
Anxiety Disorder 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For instance, our primate studies have demonstrated that activation of D1LRs in GPi and SNr leads to an inhibition of firing, most likely explained through increased GABA release in these nuclei.
Spec (likely) Negative_regulation (inhibition) of Positive_regulation (activation) of GPi associated with gaba
1) Confidence 0.18 Published 2010 Journal Frontiers in Neuroanatomy Section Body Doc Link PMC2987554 Disease Relevance 0 Pain Relevance 0.27

General Comments

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