INT344313

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Context Info
Confidence 0.09
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.80
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell morphogenesis (PDPN) embryo development (PDPN) cytoplasm (VEGFA)
cell proliferation (PDPN) signal transduction (PDPN) extracellular space (VEGFA)
Anatomy Link Frequency
body 1
PDPN (Homo sapiens)
VEGFA (Homo sapiens)
Pain Link Frequency Relevance Heat
anesthesia 1 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 82 98.12 Very High Very High Very High
Metastasis 25 95.24 Very High Very High Very High
Skin Cancer 17 91.92 High High
Malignant Neoplastic Disease 14 82.00 Quite High
Breast Cancer 1 15.76 Low Low
Small Cell Lung Carcinoma 2 5.00 Very Low Very Low Very Low
Germ Cell And Embryonal Neoplasms 1 5.00 Very Low Very Low Very Low
Respiratory Failure 1 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 1 5.00 Very Low Very Low Very Low
Adenocarcinoma 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The body of our findings is that podoplanin in LSCCs can induce VEGF-C downregulation via the JNK signaling pathway(s), and can impair tumor-associated lymphangiogenesis and lymphogenous metastasis
podoplanin Positive_regulation (induce) of VEGF in body associated with cancer and metastasis
1) Confidence 0.09 Published 2010 Journal Mol Cancer Section Body Doc Link PMC2987985 Disease Relevance 0.80 Pain Relevance 0

General Comments

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