INT344318

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Context Info
Confidence 0.11
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.92
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell morphogenesis (PDPN, RHOA) plasma membrane (PDPN, RHOA) cell cycle (PDPN, RHOA)
cell differentiation (RHOA) mitochondrion (RHOA) intracellular (RHOA)
Anatomy Link Frequency
MDCK 2
PDPN (Homo sapiens)
RHOA (Homo sapiens)
Pain Link Frequency Relevance Heat
anesthesia 1 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Breast Cancer 1 94.96 High High
Cancer 82 85.24 High High
Malignant Neoplastic Disease 14 73.76 Quite High
Metastasis 25 69.56 Quite High
Adenocarcinoma 1 55.68 Quite High
Skin Cancer 17 54.92 Quite High
Lung Cancer 1 53.04 Quite High
Small Cell Lung Carcinoma 2 5.00 Very Low Very Low Very Low
Germ Cell And Embryonal Neoplasms 1 5.00 Very Low Very Low Very Low
Respiratory Failure 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For example, although podoplanin can induce RhoA activation and an epithelial-mesenchymal transition (EMT) in MDCK cells [29], it attenuated RhoA activity and could not induce EMT in a breast carcinoma cell line [27], suggesting that podoplanin exerts cell type-specific functions.
podoplanin Positive_regulation (induce) of Positive_regulation (activation) of RhoA in MDCK associated with breast cancer
1) Confidence 0.11 Published 2010 Journal Mol Cancer Section Body Doc Link PMC2987985 Disease Relevance 0.92 Pain Relevance 0

General Comments

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