INT344319

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Context Info
Confidence 0.35
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.50
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (MAPK8) mitochondrion (MAPK8) cell morphogenesis (PDPN)
embryo development (PDPN) response to stress (MAPK8) cytoplasm (MAPK8)
MAPK8 (Homo sapiens)
PDPN (Homo sapiens)
Pain Link Frequency Relevance Heat
anesthesia 1 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Skin Cancer 17 93.20 High High
Cancer 82 80.96 Quite High
Metastasis 25 64.48 Quite High
Malignant Neoplastic Disease 14 56.00 Quite High
Small Cell Lung Carcinoma 2 5.00 Very Low Very Low Very Low
Germ Cell And Embryonal Neoplasms 1 5.00 Very Low Very Low Very Low
Respiratory Failure 1 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 1 5.00 Very Low Very Low Very Low
Adenocarcinoma 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Taken together, these findings suggest that JNK is a key pathway for inducing podoplanin-mediated downregulation of the VEGF-C gene in LSCCs.


JNK Positive_regulation (inducing) of podoplanin
1) Confidence 0.35 Published 2010 Journal Mol Cancer Section Body Doc Link PMC2987985 Disease Relevance 0.50 Pain Relevance 0

General Comments

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