INT344365

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Context Info
Confidence 0.61
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.01
Pain Relevance 0.92

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Il1a) extracellular space (Il1a) extracellular region (Il1a)
Il1a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
nMDA receptor 3 99.72 Very High Very High Very High
Opioid 13 98.10 Very High Very High Very High
Pain 77 97.14 Very High Very High Very High
Analgesic 23 96.18 Very High Very High Very High
Spinal cord 8 86.64 High High
antagonist 5 72.96 Quite High
Cholecystokinin 3 71.48 Quite High
Inflammation 10 5.00 Very Low Very Low Very Low
B1 receptor 9 5.00 Very Low Very Low Very Low
Neuropathic pain 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pain 80 97.14 Very High Very High Very High
Cancer 76 96.88 Very High Very High Very High
Pancreatic Cancer 17 87.60 High High
INFLAMMATION 12 5.00 Very Low Very Low Very Low
Neuropathic Pain 9 5.00 Very Low Very Low Very Low
Skin Cancer 8 5.00 Very Low Very Low Very Low
Hyperalgesia 3 5.00 Very Low Very Low Very Low
Bone Cancer 2 5.00 Very Low Very Low Very Low
Nociception 2 5.00 Very Low Very Low Very Low
Toxicity 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Here, we investigated the mechanism of analgesic action of Z-360 in a severe cancer-induced pain model in mice, which is considered to be opioid-resistant, by examining ephrin B1 gene expression, N-methyl-D-aspartate receptor NR2B subunit phosphorylation, and interleukin-1?
Phosphorylation (phosphorylation) of interleukin-1 associated with pain, cancer, nmda receptor, analgesic and opioid
1) Confidence 0.61 Published 2010 Journal Mol Pain Section Abstract Doc Link PMC2987997 Disease Relevance 1.01 Pain Relevance 0.92

General Comments

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