INT344381

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.17
Pain Relevance 0.93

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Grin2b) signal transduction (Olfr360) plasma membrane (Grin2b)
embryo development (Grin2b) signal transducer activity (Olfr360)
Olfr360 (Mus musculus)
Grin2b (Mus musculus)
Pain Link Frequency Relevance Heat
Spinal cord 8 99.40 Very High Very High Very High
Pain 77 95.08 Very High Very High Very High
nMDA receptor 3 90.36 High High
Opioid 13 87.12 High High
antagonist 5 85.68 High High
Analgesic 23 83.28 Quite High
Cholecystokinin 3 62.40 Quite High
Inflammation 10 5.00 Very Low Very Low Very Low
B1 receptor 9 5.00 Very Low Very Low Very Low
Neuropathic pain 5 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 76 96.08 Very High Very High Very High
Pain 80 95.08 Very High Very High Very High
Pancreatic Cancer 17 78.52 Quite High
INFLAMMATION 12 5.00 Very Low Very Low Very Low
Neuropathic Pain 9 5.00 Very Low Very Low Very Low
Skin Cancer 8 5.00 Very Low Very Low Very Low
Hyperalgesia 3 5.00 Very Low Very Low Very Low
Bone Cancer 2 5.00 Very Low Very Low Very Low
Nociception 2 5.00 Very Low Very Low Very Low
Toxicity 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Z-360 treatment inhibited both ephrin B1 gene expression and the phosphorylation of NR2B.
Z-360 Negative_regulation (inhibited) of Gene_expression (expression) of NR2B
1) Confidence 0.01 Published 2010 Journal Mol Pain Section Abstract Doc Link PMC2987997 Disease Relevance 1.17 Pain Relevance 0.93

General Comments

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