INT344387

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.05
Pain Relevance 0.66

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

pigmentation (Tyr) cell proliferation (Tyr) cell differentiation (Efnb2)
oxidoreductase activity (Tyr) cell adhesion (Efnb2) plasma membrane (Efnb2)
Anatomy Link Frequency
spinal cord 2
Efnb2 (Mus musculus)
Tyr (Mus musculus)
Pain Link Frequency Relevance Heat
Spinal cord 8 96.08 Very High Very High Very High
Pain 77 94.12 High High
B1 receptor 9 85.32 High High
Analgesic 23 66.16 Quite High
Inflammation 10 33.92 Quite Low
nMDA receptor 3 12.16 Low Low
Opioid 13 5.00 Very Low Very Low Very Low
Neuropathic pain 5 5.00 Very Low Very Low Very Low
antagonist 5 5.00 Very Low Very Low Very Low
Cholecystokinin 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 76 94.72 High High
Pain 80 94.12 High High
Skin Cancer 8 59.04 Quite High
Pancreatic Cancer 17 50.00 Quite Low
INFLAMMATION 12 33.92 Quite Low
Neuropathic Pain 9 5.00 Very Low Very Low Very Low
Hyperalgesia 3 5.00 Very Low Very Low Very Low
Bone Cancer 2 5.00 Very Low Very Low Very Low
Nociception 2 5.00 Very Low Very Low Very Low
Toxicity 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As it has been reported that ephrin B2 induces phosphorylation of Tyr-1472 residues [14], we next investigated whether Tyr-1472 phosphorylation of NR2B was enhanced in the spinal cord of the mouse model of cancer-induced pain.
ephrin B2 Positive_regulation (induces) of Phosphorylation (phosphorylation) of Tyr-1472 in spinal cord associated with pain, cancer and spinal cord
1) Confidence 0.01 Published 2010 Journal Mol Pain Section Body Doc Link PMC2987997 Disease Relevance 1.05 Pain Relevance 0.66

General Comments

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