INT344399

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Context Info
Confidence 0.03
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.59
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL8, Crp) signal transduction (IL8) extracellular region (IL8)
intracellular (IL8)
IL8 (Homo sapiens)
Crp (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 1 99.74 Very High Very High Very High
Inflammatory response 2 99.24 Very High Very High Very High
metalloproteinase 1 84.76 Quite High
Inflammation 9 53.24 Quite High
cINOD 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 12 99.06 Very High Very High Very High
Atherosclerosis 7 91.28 High High
Death 1 86.88 High High
Diabetes Mellitus 14 50.00 Quite Low
Disease 3 36.32 Quite Low
Cardiovascular Disease 7 34.64 Quite Low
Nicotine Addiction 2 10.00 Low Low
Autoimmune Disease 2 5.00 Very Low Very Low Very Low
Atherosclerotic Plaque 1 5.00 Very Low Very Low Very Low
Overweight 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, ROS can activate the transcription factor NF-kB, that is ubiquitously expressed and mediates the expression of genes involved in the acute inflammatory response, including the cytokines IL1-IL6 and IL8 [23], which in turn modulate CRP production.
IL8 Regulation (modulate) of Gene_expression (production) of CRP associated with inflammatory response and cytokine
1) Confidence 0.03 Published 2010 Journal Cardiovasc Diabetol Section Body Doc Link PMC2987999 Disease Relevance 0.59 Pain Relevance 0.20

General Comments

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