INT344401

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Context Info
Confidence 0.01
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 3.21
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Spp1) signal transduction (Agtr2) extracellular region (Spp1)
cell adhesion (Spp1) plasma membrane (Agtr2) transcription factor binding (Agtr2)
Anatomy Link Frequency
podocytes 3
mesangial cells 1
Agtr2 (Mus musculus)
Spp1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 20 5.00 Very Low Very Low Very Low
cytokine 12 5.00 Very Low Very Low Very Low
rheumatoid arthritis 6 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
Angina 2 5.00 Very Low Very Low Very Low
Glutamate 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 134 97.20 Very High Very High Very High
Coronary Artery Disease 72 96.72 Very High Very High Very High
Renal Disease 54 96.40 Very High Very High Very High
Adhesions 6 95.56 Very High Very High Very High
Albuminuria 8 69.28 Quite High
Targeted Disruption 4 64.40 Quite High
Keloid Scars 2 44.08 Quite Low
Renal Failure 2 35.92 Quite Low
Renal Insufficiency 26 12.84 Low Low
INFLAMMATION 20 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Previous studies have shown that advanced glycation end-products and angiotensin II can stimulate OPN synthesis by a variety of cells, including mesangial cells and podocytes, and initiate local effects of cell spreading, adhesion, and proliferation [28-30].
angiotensin II Positive_regulation (stimulate) of Gene_expression (synthesis) of OPN in podocytes associated with adhesions
1) Confidence 0.01 Published 2010 Journal Cardiovasc Diabetol Section Body Doc Link PMC2988001 Disease Relevance 1.60 Pain Relevance 0
Previous studies have shown that advanced glycation end-products and angiotensin II can stimulate OPN synthesis by a variety of cells, including mesangial cells and podocytes, and initiate local effects of cell spreading, adhesion, and proliferation [28-30].
angiotensin II Positive_regulation (stimulate) of in mesangial cells Gene_expression (synthesis) of OPN in podocytes associated with adhesions
2) Confidence 0.00 Published 2010 Journal Cardiovasc Diabetol Section Body Doc Link PMC2988001 Disease Relevance 1.60 Pain Relevance 0

General Comments

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