INT344405

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Context Info
Confidence 0.09
First Reported 2010
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.34
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (EGFR, Spp1) extracellular space (EGFR, Spp1) extracellular region (EGFR, Spp1)
endosome (EGFR) cell morphogenesis (EGFR) Golgi apparatus (EGFR)
EGFR (Homo sapiens)
Spp1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 10 5.00 Very Low Very Low Very Low
cytokine 6 5.00 Very Low Very Low Very Low
rheumatoid arthritis 3 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
Angina 1 5.00 Very Low Very Low Very Low
Glutamate 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetes Mellitus 67 100.00 Very High Very High Very High
Renal Insufficiency 13 95.40 Very High Very High Very High
Coronary Artery Disease 36 58.52 Quite High
Renal Disease 27 58.20 Quite High
INFLAMMATION 10 5.00 Very Low Very Low Very Low
Atherosclerosis 7 5.00 Very Low Very Low Very Low
Albuminuria 4 5.00 Very Low Very Low Very Low
Adhesions 3 5.00 Very Low Very Low Very Low
Cardiovascular Disease 3 5.00 Very Low Very Low Very Low
Diabetes Complications 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition, there was a negative correlation found between OPN, but not N-half OPN, and eGFR in T2DM patients (r = -0.258; P < 0.001; Figure 1A), as well as stepwise increases in mean OPN concentrations in patients with deteriorating renal function (237 ± 72, 268 ± 120, and 338 ± 203 ng/mL in T2DM patients with normal, mild, moderate renal insufficiency, respectively; P < 0.001; Figure 1B).
eGFR Binding (found) of OPN associated with diabetes mellitus and renal insufficiency
1) Confidence 0.09 Published 2010 Journal Cardiovasc Diabetol Section Body Doc Link PMC2988001 Disease Relevance 1.34 Pain Relevance 0

General Comments

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